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Margaret A. Keller, M.D.

Margaret A. Keller, M.D.

Margaret A. Keller, M.D.
Division Chief, Division of Pediatric Infectious Diseases
Professor of Pediatrics, Division of Allergy and Immunology

Contact Information:
1000 West Carson St.
Box 467
Torrance, CA 90509

Phone: (310) 781-3636
Fax: (310) 972-2962
Email: keller@labiomed.org

Research Focus:
Magnetic resonance spectroscopy of the brain in HIV-infected patients. Clinical trials in HIV–infected children, adolescents, and pregnant woman including pharmacokinetics of antiretroviral drugs and prevention of maternal to infant transmission of HIV.

Certifications:
American Board of Pediatrics
American Board of Pediatrics, Subspecialty Board
Pediatric Infectious Diseases

Training:
Internship, Residency and Chief Resident in Pediatrics, University Hospital, University of California, San Diego
Fellowship in Pediatric Infectious Diseases, University of California, San Diego
Fellowship in Pediatric Infectious Diseases and Immunology, Harbor-UCLA Medical Center, Torrance, CA

Education:
M.D., Albert Einstein College of Medicine of Yeshiva University, Bronx, NY

Selected Publications:

1. Dickover, R.E., Garraty, E.M., Herman, S.A., Sim, M., Plaeger, S., Boyer, P.J., Keller, M.A., Deveikis, A., Stiehm, E.R., Bryson, Y.J.: Identification of levels of Maternal HIV-1 RNA associated with risk of perinatal transmission: Effect of maternal zidovudine treatment on viral load. JAMA, 275(8):599-605, 1996.

2. Jelonek, M.T., Maskrey, J.L., Steimer, K.S., Potts, B.J., Higgins, K.W., Keller, M.A.: Maternal Monoclonal Antibody to V-3 Loop Alters Specificity of the Response to a Human Immunodeficiency Virus Vaccine. Journal of Infectious Diseases, 174:866-869, 1996.

3. Jelonek, M.T., Maskrey, J.L., Cummins, L.J., Arora, Y., Steimer, K. S., White-Scharf, M., Keller, M.A. Human Immunodeficiency Virus Hyperimune Globulin (HIVIG) or Intravenous Immune Globulin (IVIG) Inhibits Response to an HIV Vaccine. Biotechnol. Appl. Biochem., 27:89-95, 1998.

4. Dickover, R.E., Dillon, M., Leung, K.M., Korgstad, P., Plaeger, S., Kwok, S., Christopherson, C., Deveikis, A., Keller, M.A., Stiehm, E.R., Bryson, Y.J. Early Prognostic Indicators in Primary Perinatal Human Immunodeficiency Virus Type 1 Infection: Importance of Viral RNA and the Timing of Transmission on Long-Term Outcome. The Journal of Infectious Diseases, 178:375-87, 1998.

5. Keller, M.A., Arora Y. Inhibition of the anti-V3 loop response to a rgp120SF2 vaccine by preexisting monoclonal antibody. AIDS Research and Human Retroviruses, 15:855-860, 1999.

6. Yeh, S. H., Zangwill, K. M., Hall, B., McPhaul, L., Keller, M.A. Parapharyngeal abscess due to cat scratch disease. Clinical Infectious Disease, 30:599-601, 2000.

7. Keller, M.A., Deveikis, A., Cutillar-Garcia, M., Gagajena, A., Elkins, K., Plaeger, S., Chang S-J., Bryson, Y., Kaplan, A., Zangwill, K. Pneumococcal and Influenza Immunization and HIV Viral Load in Children. Pediatric Infectious Diseases Journal 19:613-618, 2000.

8. Keller, M.A., Stiehm, E. R. Passive Immunity in Prevention and Treatment of Infectious Diseases. Clinical Microbiology Reviews 13:602-614, 2000.

9. Purdy, K.W., Heckenlively, J.R., Church, J.A., Keller, M.A. Progressive outer retinal necrosis caused by Varicella-Zoster Virus in children with acquired immunodeficiency syndrome. The Pediatric Infectious Disease Journal 22:1-3, 2003.

10. Keller, M.A., Venkatraman, T.N., Thomas, A., Deveikis, A., LoPresti, C., Hayes, J., Berman, N., Walot, I., Padilla, D., Johnston-Jones, J. Ernst, T., Chang, L. Altered neurometabolite development in HIV + children: correlation with neuropsychological tests. Neurology 2004 May 25;62(10):1810-7.

11. Zhao, X., Sun, N.C.J., Witt, M.D., Keller, M.A., and Niihara, Y. Changing Pattern of AIDS: A bone marrow study. Am J Clin Pathol. 121:393-401, 2004.

12. Mirochnick, M., Stek, A., Acevedo, M., Keller, M.A., Holland, D., Capparelli, E., Connor, J., Huang, M.S., Hughes, M., Watts, H., Mofenson, L., Bryson, Y. Safety and pharmacokinetics of nelfinavir coadministered with zidovudine and lamivudine in infants during the first 6 weeks of life. J Acquir Immune Defic Syndr 39(2):189-194, June 1, 2005.

13. Keller, M.A., Venkatraman, T.N., Thomas, M.A., Deveikis, A., LoPresti, C., Hayes, J., Berman, N., Walot, I., Ernst, T., Chang, L. Cerebral Metabolites in HIV-infected children followed for ten months with 1H-MRS. Neurology 66(6):874-9 Mar 2006.

14. Banakar,S., Thomas, M.A., Deveikis,A., Watzl, J.Q.Y., Hayes, J., and Keller, M.A. Two- Dimensional 1H-MR spectroscopy othe Brain in HIV-Infected Children. J Magn Reson Imaging. 2008 Apr;27(4):710-7.

15. Bryson, Y.J., Mirochnick, M., Stek, A., Mofenson, L.M., Connor, J., Capparelli, E., Watts, D.H., Juang, S., Hughes, M.D., Kaiser, K., Purdue, L., Asfaw, Y., Keller, M. and Smith, E. for the PACTG 353 Team: Pharmacokinetics and Safety of Nelfinavir When Used in Combination with Zidovudine and Lamivudine in HIV-Infected Pregnant Women; Pediatric AIDS clinical Trials Group (PACTG) Protocol 353. HIV Clinical Trials, In press.

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