Harbor-UCLA Pediatrics

eLearning Login

Lynne Smith, M.D., F.A.A.P.

Dr. Lynne Smith

Lynne Smith, M.D., F.A.A.P.
Professor of Clinical Pediatrics
Division of Neonatology
Director, Level II Nursery
Director, Perinatal Clinical Research Center
Associate Program Director, Neonatal-Perinatal Medicine Fellowship Training Program
Vice-Chair, Academic Affairs, Department of Pediatrics
Co-Director, Medical Student Education, Department of Pediatrics
Investigator of Clinical and Community Research Resources Program, Clinical Translational Science Institute

Contact Information:
1124 West Carson Street
RB-1, Box 446
Torrance, CA 90502-2064

Phone: (310) 222-1968
Fax: (310) 222-3887
Email: smith@labiomed.org

Research Focus:
The primary focus of my research efforts is to determine the effects of prenatal drug exposure on the developing brain. In collaboration with colleagues I have utilized non-invasive brain imaging techniques in children exposed to drugs in utero. In addition, I have been a collaborative investigator for the Infant Development Environment and Lifestyle (IDEAL) study, a longitudinal study addressing many aspects of prenatal methamphetamine exposure. Collectively, these efforts are intended to develop appropriate interventions for exposed children and their families.

Certifications:
Board of Medical Quality Assurance, State of California
Diplomate, American Board of Pediatrics
Diplomate, American Board of Pediatrics- Neonatal and Perinatal Medicine
Drug Enforcement Agency

Training:
Pediatric Internship and Residency, Harbor-UCLA Medical Center
Neonatal-Perinatal Medicine Fellowship, Harbor-UCLA Medical Center

Education:
B.S., Biological Sciences, University of California, Irvine
M.D., University of California, Davis

Selected Publications:

Selected Publications:

1. Smith LM, LaGasse LL, Derauf C, Newman E, Shah R, Haning W, Arria A, Huestis M, Strauss A, Della Grotta S, Dansereau LM, Lin H, Lester BM. Motor and cognitive outcomes through three years of age in children exposed to prenatal methamphetamine. Neurotoxicol Teratol. 2011 Jan-Feb;33(1):176-84. PMID: 21256431

2. Derauf C, LaGasse L, Smith L, Newman E, Shah R, Arria A, Huestis M, Haning W, Strauss A, Della Grotta S, Dansereau L, Lin H, Lester B. Infant temperament and high-risk environment relate to behavior problems and language in toddlers. J Dev Behav Pediatr. 2011 Feb-Mar;32(2):125-35. PMID: 21200329

3. Wang GJ, Smith L, Volkow ND, Telang F, Logan J, Tomasi D, Wong CT, Hoffman W, Jayne M, Alia-Klein N, Thanos P, Fowler JS. Decreased dopamine activity predicts relapse in methamphetamine abusers. Mol Psychiatry. 2012 Sep;17(9):918-25. doi: 10.1038/mp.2011.86. Epub 2011 Jul 12. PMID: 21747399

4. Zabaneh R, Smith LM, LaGasse LL, Derauf C, Newman E, Shah R, Arria A, Huestis M, Haning W, Strauss A, Della Grotta S, Dansereau LM, Lin H, Neal C, Lester BM. The effects of prenatal methamphetamine exposure on childhood growth patterns from birth to 3 years of age. Am J Perinatol. 2012 Mar;29(3):203-10. Epub 2011 Aug 4. PMID: 21818727

5. Purdy IB, Smith L, Wiley D, Badr L. A Psychoneuroimmunologic Examination of Cumulative Perinatal Steroid Exposures and Preterm Infant Behavioral Follow-Up. Biol Res Nurs. 2011 Sep 7. [Epub ahead of print] PMID: 21900308

6. Derauf C, Lagasse LL, Smith LM, Newman E, Shah R, Neal CR, Arria AM, Huestis MA, Dellagrotta S, Dansereau LM, Lin H, Lester BM. Prenatal Methamphetamine Exposure and Inhibitory Control among Young School-Age Children. J Pediatr. 2012 Mar 15. PMID: 22424953

7. Lagasse LL, Derauf C, Smith LM, Newman E, Shah R, Neal C, Arria A, Huestis MA, Dellagrotta S, Lin H, Dansereau LM, Lester BM. Prenatal Methamphetamine Exposure and Childhood Behavior Problems at 3 and 5 Years of Age. Pediatrics. 2012 Mar 19. PMID: 22430455

8. Roussotte FF, Rudie JD, Smith L, O'Connor MJ, Bookheimer SY, Narr KL, Sowell ER. Frontostriatal Connectivity in Children during Working Memory and the Effects of Prenatal Methamphetamine, Alcohol, and Polydrug Exposure. Dev Neurosci. 2012 Mar 29. PMID: 22472800

9. Smith LM, Paz MS, Lagasse LL, Derauf C, Newman E, Shah R, Arria A, Huestis MA, Haning W, Strauss A, Della Grotta S, Dansereau LM, Neal C, Lester BM. Prenatal exposure to methamphetamine and maternal depression: neurodevelopmental findings from the Infant Development, Environment, and Lifestyle (IDEAL) Study. Depress Anxiety. 2012 May 3. doi: 10.1002/da.21956. PMID: 22555777

10. Liles BD, Newman E, Lagasse LL, Derauf C, Shah R, Smith LM, Arria AM, Huestis MA, Haning W, Strauss A, Dellagrotta S, Dansereau LM, Neal C, Lester BM. Perceived Child Behavior Problems, Parenting Stress, and Maternal Depressive Symptoms Among Prenatal Methamphetamine Users. Child Psychiatry Hum Dev. 2012 May 3. PMID: 22552952

11. Wu M, Lagasse LL, Wouldes TA, Arria AM, Wilcox T, Derauf C, Newman E, Shah R, Smith LM, Neal CR, Huestis MA, Dellagrotta S, Lester BM. Predictors of Inadequate Prenatal Care in Methamphetamine-Using Mothers in New Zealand and the United States. Matern Child Health J. 2012 May 16. PMID: 22588827

12. Shah R, Diaz SD, Arria A, Lagasse LL, Derauf C, Newman E, Smith LM, Huestis MA, Haning W, Strauss A, Della Grotta S, Dansereau LM, Roberts MB, Neal C, Lester BM. Prenatal methamphetamine exposure and short-term maternal and infant medical outcomes. Am J Perinatol. 2012 May;29(5):391-400. PMID: 22399214

13. Wouldes TA, Lagasse LL, Derauf C, Newman E, Shah R, Smith LM, Arria AM, Huestis MA, Dellagrotta S, Wilcox T, Neal CR Jr, Lester BM. Co-morbidity of substance use disorder and psychopathology in women who use methamphetamine during pregnancy in the US and New Zealand. Drug Alcohol Depend. 2012 Jul 10. [Epub ahead of print] PMID: 22789630

14. Colby JB, Smith L, O’Connor MJ, Bookheimer SY, Van Horn JD, Sowell ER. White matter microstructural alterations in children with prenatal methamphetamine/polydrug exposure. Psychiatry Research: Neuroimaging (In Press).

15. Abar B, Lagasse LL, Derauf C, Newman E, Shah R, Smith LM, Arria A, Huestis M, Della Grotta S, Dansereau LM, Neal C, Lester BM. Examining the relationships between prenatal methamphetamine exposure, early adversity, and child neurobehavioral disinhibition. Psychology of Addictive Behaviors (In press).

Pubmed Search:
PubMed Search for Lynne M. Smith